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Sildenafil is a strong and selective inhibitor of cGMP-unique phosphodiesterase form five (PDE5), which is chargeable for degradation of cGMP from the corpus cavernosum. The molecular construction of sildenafil is analogous to that of cGMP and acts for a aggressive binding agent of PDE5 in the corpus cavernosum, leading to much more cGMP and increa
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